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    Alice Viotti, PhD (she/her/hers)

    Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    Alice Viotti, Ph.D.
    Postdoctoral Research Fellow, Cutaneous Biology Research Center, Massachusetts General Hospital / Harvard Medical School

    Alice Viotti is a translational researcher with broad training in molecular medicine, neuroscience, and energy-based therapeutics. Her work bridges mechanistic laboratory science with clinically relevant questions, with a current focus on how controlled energy delivery shapes biological responses in skin and systemic physiology.
    She earned her bachelor's and master's degrees at the University of Pavia (Italy), where she investigated antioxidant-based strategies for ischemic stroke, and completed her Ph.D. in Molecular Medicine at the San Raffaele Scientific Institute in Milan, studying autophagy modulation as a therapeutic approach to improve brain recovery following cerebral ischemia. During her doctoral training, she developed a preclinical chemical screening pipeline to identify and validate autophagy modulators with neuroprotective potential — work presented at the Keystone Symposia and the EMBO Workshop on Autophagy, and published as a first-author article in Autophagy.
    At Massachusetts General Hospital, Dr. Viotti pursued two complementary postdoctoral experiences centered on energy-based interventions. At the Depression Clinical and Research Program (DCRP), she contributed to clinical trials and translational studies investigating whole-body hyperthermia as a non-pharmacological intervention, gaining hands-on experience in human research, clinical trial execution, and biomarker-oriented translational analysis. This work informed her understanding of how systemic energy delivery engages biological pathways beyond the site of application — a conceptual thread that runs through her current research.
    She subsequently joined the Cutaneous Biology Research Center (CBRC) under the mentorship of Dr. Dieter Manstein, where her research investigates how parameters of energy delivery shape transcriptional, metabolic, inflammatory, and mitochondrial responses in skin, with the goal of linking controlled laser-tissue interaction to mechanistically grounded treatment optimization.
    Her methodological repertoire spans RNA sequencing and transcriptomic analysis, GSEA, cytokine profiling, epigenetic aging clocks, mitochondrial DNA analysis, ex vivo tissue treatment and processing for molecular analysis, and in vivo experimental modeling. She has contributed to peer-reviewed publications, including original research on energy-based and metabolic interventions (JID Innovations, 2026; DOI: 10.1016/j.xjidi.2026.100474), and an Autophagy manuscript (PMID: 41787744).
    Dr. Viotti is committed to rigorous, collaborative, and inclusive science. She values interdisciplinary approaches and mentorship grounded in effective communication and trainee support. As an international fellow, she brings a cross-cultural perspective to her research environment and to the broader scientific community.

    Presentation(s):